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Table 2 Stages of chronic aortic regurgitation

From: 2023 Korean Society of Echocardiography position paper for diagnosis and management of valvular heart disease, part I: aortic valve disease

Characteristic

Stage

 

A

B

C1

C2

D

Definition

At risk

Progressive

Asymptomatic severe

Symptomatic severe

Severity

Normal to none

Mild

Moderate

Severe

Echocardiography

   

 Morphology

   

  Leaflet

Congenital, BAV, sclerosis

Calcification or rheumatic changes

Severe calcification or rheumatic changes

  Sinus/ascending aorta

-

Dilated

Dilated

 Vena contracta width (mm)

-

<3

3–6

≥6

 Jet width (% of LVOT)

-

<25

25–64

≥65

 JCSA (% of LVOT)

-

<5

5–59

≥60

 EROA (cm2)

-

<0.1

0.1–0.3

≥0.3

 Regurgitant volume (mL)

-

<30

30–59

≥60

 Regurgitant fraction (%)

-

<30

30–49

≥50

 Diastolic flow reversalb

-

Brief, early

Intermediate

Holodiastolic (end-diastolic velocity >20 cm/sec)

 LVEF (%)

Normal

Normal

>50

≤50

Any

 LVESD (mm)

Normal

Normal

<50

>50 (25a)

Dilation ↑↑

Symptom

None

None

None

DOE, Angina, HF

  1. BAV Bicuspid aortic valve, LVOT Left ventricular outflow tract, JCSA Jet cross section area, EROA Effective regurgitant orifice area by two-dimensional proximal isovelocity surface area method, LVEF Left ventricular ejection fraction, LVESD Left ventricular endsystolic dimension, DOE Dyspnea on exertion, HF Heart failure
  2. aLVESD index (mm/m2)
  3. bDoppler flow in the descending aorta