Characteristic | Stage | |||||
---|---|---|---|---|---|---|
 | A | B | C1 | C2 | D | |
Definition | At risk | Progressive | Asymptomatic severe | Symptomatic severe | ||
Severity | Normal to none | Mild | Moderate | Severe | ||
Echocardiography | Â | Â | Â | |||
 Morphology |  |  |  | |||
  Leaflet | Congenital, BAV, sclerosis | Calcification or rheumatic changes | Severe calcification or rheumatic changes | |||
  Sinus/ascending aorta | - | Dilated | Dilated | |||
 Vena contracta width (mm) | - | <3 | 3–6 | ≥6 | ||
 Jet width (% of LVOT) | - | <25 | 25–64 | ≥65 | ||
 JCSA (% of LVOT) | - | <5 | 5–59 | ≥60 | ||
 EROA (cm2) | - | <0.1 | 0.1–0.3 | ≥0.3 | ||
 Regurgitant volume (mL) | - | <30 | 30–59 | ≥60 | ||
 Regurgitant fraction (%) | - | <30 | 30–49 | ≥50 | ||
 Diastolic flow reversalb | - | Brief, early | Intermediate | Holodiastolic (end-diastolic velocity >20 cm/sec) | ||
 LVEF (%) | Normal | Normal | >50 | ≤50 | Any | |
 LVESD (mm) | Normal | Normal | <50 | >50 (25a) | Dilation ↑↑ | |
Symptom | None | None | None | DOE, Angina, HF |