Characteristic | Rheumatic MS | MAC-related degenerative MS |
---|---|---|
Anatomy | Funnel-shaped geometry | Tubular orifice geometry |
Commissural fusion | Commissures spared | |
Epidemiology | Younger population | Elderly, comorbid population |
Echo assessment | MVA quantification validated | MVA quantification challenging |
 | Greater MVA relative to mean gradient than rheumatic MS | |
Treatment | PMV if favorable valve morphology without contraindication | Poor valvuloplasty candidates |
MV replacement | Transcatheter or surgical MV replacement |