Characteristic | Stage | ||||
---|---|---|---|---|---|
 | A | B | C | D | |
Definition | At risk | Progressive | Asymptomatic severe | Symptomatic severe | |
Severity | Normal to insignificant | Mild | Moderate | Severe | |
Echocardiography morphology | |||||
 Leaflet | Mildly fibrotic or sclerotic, mild doming | Partial fibrothickening, sclerocalcified, doming | Severe fibrothickening, sclerocalcified, doming | ||
 Commissure | No fusion | Mild to moderate fusion | Severe fusion | ||
 Annulus | Mild calcification | Mild to moderate calcification | Severe calcification | ||
Area (cm2) | - | > 2.5 | 1.6–2.5 | ≤ 1.5 (very severe, ≤ 1.0) | |
MDPG (mmHg) | - | < 3 | 3–5 | ≥ 5 (very severe, ≥ 10) | |
PHT (msec) | - | < 100 | 100–149 | ≥ 150 | |
PASP (mmHg) | Normal | Normal | Normal at rest | Normal at rest or > 50 | > 50 |
LA size | Normal | Normal or ↑ | ↑ | ↑ | |
Symptom | None | None | None | DOE, EI |