Global and regional cardiac magnetic resonance feature tracking left ventricular strain analysis in assessing early myocardial disease in β thalassemia major patients

Table 3 Comparison of cardiac magnetic resonance imaging parameters and LV global myocardial strain values in β-thalassemia major patients with and without MIO

Parameter	Without MIO (n = 46)	With MIO (n = 11)	P-value
LV EF (%)	60.0 ± 4.7	58.8 ± 4.8	0.423
LV EDVI (mL/m²)	109.9 ± 21.7	89.2 ± 15.5	0.007^*
LV ESVI (mL/m²)	44.1 ± 11.4	36.2 ± 7.1	0.013^*
LV SV (mL)	107.6 ± 22.8	83.9 ± 18.6	0.002^*
LV EDWMI	44.1 ± 30.2	44.5 ± 22.0	0.966
LV EDWM to EDV ratio	0.4 ± 0.3	0.5 ± 0.2	0.224
T2* (msec)	38.4 ± 10.9	11.4 ± 3.4	< 0.001^*
Myocardial iron concentration (mg/g)	0.6 ± 0.2	2.6 ± 0.9	< 0.001^*
LV GLS (%)	–17.3 ± 2.2	–16.9 ± 2.0	0.678
LV GCS (%)	–15.8 ± 2.1	–16.1 ± 1.6	0.572
LV GRS (%)	25.6 ± 4.8	26.1 ± 3.4	0.771

Values are presented as mean ± standard deviation. Student t-test was used to test significance
LV Left ventricle, MIO Myocardial iron overload, EF Ejection fraction, EDVI End-diastolic volume index, ESVI End-systolic volume index, SV Stroke volume, EDWMI End-diastolic wall mass index, EDWM End-diastolic wall mass, EDV End-diastolic volume, GLS Global longitudinal strain, GCS Global circumferential strain, GRS Global radial strain
^*P < 0.05

ISSN: 2586-7296