Table 2 Clinical characteristics of the study participants
Study | Age (yr) | 6MWD (m) | BMI (kg/m2) | FEV1 (%) predicted | FEV1/FVC ratio | LV EF | S’ RV | TAPSE (cm) | PASP | RV FWS | RV SW strain | RV GLS | LV GLS |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Schoos et al. [22] (2013) | 62 to 77 | 403 ± 113 | 25.75 (21 to 28.5) | 52.07 (49.22 to 56.9) | 49.75 (44.75 to 55) | 63.9 ± 8.8 | 13.25 (11.75 to 14.25) | 2.25 (2.12 to 2.45) | 32.65 (29.37 to 38.27) | NA | NA | –23.95 (–18.9 to –30.42) | –18.4 ± 3.8 |
Gökdeniz et al. [21] (2014) | 69.6 ± 10.6 | 282.75 ± 117.1 | 25.3 ± 4.7 | 47.3 ± 17.6 | 61.1 ± 9.9 | 59.1 ± 5.4 | 11.8 ± 3.3 | 2.0 ± 0.2 | 32.2 ± 7.5 | –19.3 ± 2.2 | –19.9 ± 0.8 | NA | NA |
Kalaycıoğlu et al. [25] (2015) | 70 ± 10 | NA | 25 ± 4 | 45 ± 15 | 60 ± 9 | 59.2 ± 5.4 | 0.16 ± 0.03 | 2.3 ± 0.4 | 32.4 ± 7.6 | NA | NA | NA | –18.58 ± 3.28 |
Rice et al. [28] (2016) | 54 to 61 | NA | NA | 16 (13 to 20) | NA | 65.5 (61 to 70) | NA | NA | 44 (31.5 to 62) | –21.5 (–26 to –13.5) | NA | NA | NA |
Al Abbady et al. [20] (2018) | 62.4 ± 5.9 | NA | NA | 53 ± 17 | 54.9 ± 6 | 60.8 ± 4.6 | NA | 2.0 ± 0.2 | 37.9 ± 9.6 | NA | NA | NA | –17.38 ± 1.3 |
Kanar et al. [26] (2018) | 61.2 ± 10.1 | 337 ± 42 | 31.2 ± 9.3 | 13.4 ± 4.2 | 68% | 58.3 ± 5.1 | NA | 1.66 ± 0.2 | 50.1 ± 18 | –18.7 ± 3.9 | –20.8 ± 2.8 | NA | NA |
Kanar et al. [27] (2018) | 60.8 ± 10.2 | 326 ± 42.2 | 28.2 ± 8.4 | NA | NA | 57.7 ± 5.5 | 12.9 ± 2.93 | 1.66 ± 0.2 | 46.7 ± 15.4 | –18.1 ± 3.4 | NA | –20.4 ± 2.4 | NA |
Fahim et al. [18] (2020) | 61.2 ± 8.5 | 206 ± 95.6 | 26.8 ± 5.0 | 64 ± 17.73 | 53.8 ± 11.22 | 63.7 ± 6.6 | NA | 1.66 ± 0.3 | 20.4 ± 12.1 | –13.33 ± 7.6 | –14.80 ± 5.4 | –12.4 ± 3.6 | –16.04 ± 4.1 |
Masson Silva et al. [24] (2021) | 65.5 ± 8.9 | 427.8 ± 97.5 | 25.2 ± 5.6 | 54.5 ± 22.0 | 46.4 ± 14.5 | NA |  < 9.5: n = 6 (25%)  > 9.5: n = 67 |  < 1.7: n = 5 (21%)  > 1.7: n = 67 | 36.9 ± 17.6 | –18.98 ± 4.11 | NA | –15.48 ± 4.06 | NA |
Cengiz Elçioğlu et al. [19] (2022) | 60.2 ± 6.2 | NA | 24.9 ± 4.12 | 45.8 ± 15.9 | 55.8 ± 10.3 | 60.5 ± 1.4 | 10.96 ± 0.88 | 1.97 ± 0.11 | 31.03 ± 5.9 | NA | NA | NA | –14.76 ± 2.69 |
Botelho et al. [23] (2022) | 68.4 ± 8.3 | NA | 24.4 ± 4.2 | NA | NA | 68.9 ± 6.4 | NA | 1.8 ± 3.7 | 43.2 ± 11.02 | NA | NA | –17.2 ± 4.4 | NA |